DX® – Colon Cancer DX® Colon Cancer Molecular Test

is focused on patients with metastatic colorectal cancer (colon cancer).

The multi-gene molecular assay DX® Colon Cancer

includes the most common mutated genes in colorectal cancer, as well as genes that help determine targeted treatment options. DX® Colon is designed to achieve maximum sensitivity and specificity. All findings are classified using the most reliable and updated databases and in silico analysis algorithms. Next Generation Sequencing (NGS) technology is used for the simultaneous analysis of many genes alterations using the same sample, thus saving valuable material.

The DX® Colon test:

  • Determines the molecular profile (gene mutations) of the tumor and of interactions between genes in case of multiple mutations.
  • Designates the on-label drug (if it exists) that targets the mutated gene(s) or the pathway that the gene(s) are involved in.
  • Identifies mutations associated with resistance to targeted treatment.
  • Assigns off-label treatments or ongoing clinical trials based on tumor’s molecular profile.
    This could be particularly important for patients who have failed conventional therapy.

Table of Genes Analyzed

27 gene alterations


7 fusion transcripts


Immunotherapy Biomarkers



It is designed for patients with colorectal cancer. It can also be used in other types of solid tumors including those of unknown origin.
For the Com.Pl.i.t DX Colon Assay we need a paraffin block that contains the tumor tissue. We need one paraffin block or four unstained paraffin sections of 3μm: in positive charged slides (air dried, not baked), placed on top of the slide, without folds and six unstained slides of 10μm.
The sample should be kept at room temperature (25°C). During the summer period we recommend to have an ice pack in the Kit (The ice pack should not directly touch the samples).
For information about the cost coverage of the test you should contact your personal insurance.
The payment can be made by bank transfer or credit/debit card.
Genekor is responsible for all the necessary procedures of the pick-up and return of the patient’s specimen. To arrange your sample pick-up and return, contact us or complete the appropriate Test Order Form.
Your report will electronically be released to your physician via email and/or uploaded to our secure portal and to you via email or mail.
Genekor Medical S.A. is certified with ELOT EN ISO9001:2008 and ELOT EN ISO15189:2012, which require the written consent of each patient for the use of his/her genetic material for testing.

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